Ref: Cotoia et al. J Anesth Analg Crit Care (2022) 2:41, https://doi.org/10.1186/s44158-022-00068-1 Glutamine (GLN) is classified as a non-essential amino acid and it is released from skeletal muscle to be a constituent of proteins . Furthermore, GLN acts as an immune stimulator as an essential component for lymphocyte proliferation and cytokine production,

Ref: A. Ma, M. Dong, J. Cheng et al, Journal of Intensive Medicine 3 (2023) 65–72, https://doi.org/10.1016/j.jointm.2022.05.006 The intensive care unit (ICU) is the “hardest hit” department for hospital-acquired infections, where a range of traumatic procedures can lead to fatal infections. Ventilator-related pneumonia, catheter-related bloodstream infections caused by an arterial

Ref: Bussini L., et al, J Emerg Crit Care Med 2022;6:25 | https://dx.doi.org/10.21037/jeccm-22-32 Hospital-acquired pneumonia (HAP) and ventilator associated pneumonia (VAP) remain leading causes of morbidity and mortality despite recent advances in prevention, diagnosis, and treatment. HAP is a lung infection occurring in the nosocomial setting which develops after 48

Ref: William Durante, Nutrients 2019, 11, 2092; doi:10.3390/nu11092092 Cardiovascular disease is the primary cause of morbidity and mortality in the world, accounting  for nearly one-third of all deaths . Although the age-adjusted mortality rate for cardiovascular disease has diminished in industrialized countries owing to life- style changes, smoking cessation, advances

Ref: Raman S.,etal, The SPLYT-P Randomized Clinical Trial, JAMA Pediatr. Published online December 19, 2022. doi:10.1001/jamapediatrics.2022.4912  Importance  Most children admitted to pediatric intensive care units (PICUs) receive intravenous fluids. A recent systematic review suggested mortality benefit in critically ill adults treated with balanced solutions compared with sodium chloride, 0.9% (saline). There is

Ref: Einav L. etal. Risk Factors for Malnutrition among IBD Patients, Nutrients 2021, 13, 4098. https:// doi.org/10.3390/nu13114098 The prevalence of malnutrition in inflammatory bowel diseases (IBD) is estimated to be between 6.1% and 69.7% depending on the definition used, the type of IBD, the clinical setting and disease activity. Malnutrition

Ref: https://www.pharmacypracticenews.com/Online-First/Article/05-22/Reluctance-to-Prescribe-Supplemental-Nutrition-to-COVID-19-ICU-Patients/67144 Despite the benefits of providing early enteral nutrition (EN) and parenteral nutrition (PN) to critically ill COVID-19 patients, many physicians remain reluctant to do so, according to a survey highlighted at the American Society for Parenteral and Enteral Nutrition (ASPEN) 2022 Nutrition Science and Practice Conference. Beth Taylor,

Ref: https://www.pharmacypracticenews.com/Online-First/Article/03-22/Conservative-Dextrose-Administration-Reduces-PN-Related-Hyperglycemia-Risk/66550 Conservative rates of dextrose infusion can mitigate the risk for hyperglycemia in hospitalized adults with obesity who are receiving parenteral nutrition (PN), as shown in findings presented at the ASPEN 2022 Nutrition Science and Practice Conference. Moreover, obesity alone does not predict the likelihood of hyperglycemia during PN

Indian J Cancer. Oct-Dec 2017;54(4):685-690. Doi: 10.4103/ijc.IJC_364_17. Introduction Nosocomial infections are mainly caused by the gram-negative bacteria . The emergence of multidrug resistant (MDR) strains has led to increased mortality, morbidity and hospitalization costs. Carbapenems have been effective in treating various bacterial infections including MDR nosocomial infections. However, excessive and indiscriminate

Ref: Crit Care 24, 55 (2020). https://doi.org/10.1186/s13054-020-2763-4. Introduction The significant prevalence, increasing antimicrobial resistance and suboptimal clinical outcomes of patients with nosocomial pneumonia warrants the need for optimization of the antimicrobial dose. Meropenem, a carbapenem, is known to be effective against many pathogens causing nosocomial pneumonia. However, there is insufficient data regarding

Ref: Le Pape et al. Annals of Intensive Care (2022) 12:24, https://doi.org/10.1186/s13613-022-00998-7 Background The clinical impact and outcomes of ventilator-associated pneumonia (VAP) have been scarcely investigated in patients with the acute respiratory distress syndrome (ARDS). Methods Patients admitted over an 18-month period in two intensive care units (ICU) of a

Ref Mele, A., Cerminara, E., Häbel, H. et al. Fluid accumulation and major adverse kidney events in sepsis: a multicenter observational study. Ann. Intensive Care 12, 62 (2022). https://doi.org/10.1186/s13613-022-01040-6  Background Whether early fluid accumulation is a risk factor for adverse renal outcomes in septic intensive care unit (ICU) patients remains