Clinical efficacy and safety of linezolid in intensive care unit patients

Ref: A. Ma, M. Dong, J. Cheng et al, Journal of Intensive Medicine 3 (2023) 65–72, https://doi.org/10.1016/j.jointm.2022.05.006 The intensive care unit (ICU) is the “hardest hit” department for hospital-acquired infections, where a range of traumatic procedures can lead to fatal infections. Ventilator-related pneumonia, catheter-related bloodstream infections caused by an arterial

Diagnosis, management and treatment of nosocomial pneumonia in ICU

Ref: Bussini L., et al, J Emerg Crit Care Med 2022;6:25 | https://dx.doi.org/10.21037/jeccm-22-32 Hospital-acquired pneumonia (HAP) and ventilator associated pneumonia (VAP) remain leading causes of morbidity and mortality despite recent advances in prevention, diagnosis, and treatment. HAP is a lung infection occurring in the nosocomial setting which develops after 48

NHS in England to offer artificial pancreas to help manage type 1 diabetes

Successful trial of groundbreaking device, now approved by Nice, uses algorithm to determine amount of insulin needed More than 100,000 people with type 1 diabetes in England are to be offered an artificial pancreas, which experts believe could become the “holy grail” for managing the disease. The groundbreaking device uses an algorithm

Empagliflozin, irrespective of blood pressure, improves outcomes in heart failure with preserved ejection fraction: the EMPEROR Preserved trial

Ref: Michael Böhm, European Heart Journal (2022) 00, 1–12, https://doi.org/10.1093/eurheartj/ehac693 Empagliflozin reduced cardiovascular death and heart failure hospitalization in patients with preserved ejection fraction. Hypertension is the most common comorbidity and etiological trigger of heart failure with preserved ejection fraction (HFpEF) as pressure overload produces left ventricular hypertrophy, diastolic dysfunction,

Arterial gipertenziya uchun sakubitril / valsartan samaradorligi

Aaqib М. va boshq., Amerika terapiya jurnali 29(3):p e322-e333, May/Iyun 2022. | DOI: 10.1097/MJT.0000000000000925. Kirish: Sakubitril / valsartan (LCZ696) otib berish fraktsiyasi kamaygan holda surunkali yurak yetishmovchiligini davolash uchun tasdiqlanganidan beri eng istiqbolli dorilardan biriga aylandi. So’nggi dalillar LCZ696 bilan yuqori qon bosimini nazorat qilishni ko’rsatadi. Ma’lumotlar manbalari: LCZ696 ning

Echocardiographic Markers in the Diagnosis of Cardiac Masses

Paolisso P., et al,  Journal of the American Society of Echocardiography, Published: January 04, 2023DOI:https://doi.org/10.1016/j.echo.2022.12.022 Background The echocardiographic parameters required for a comprehensive assessment of cardiac masses (CMs) are still largely unknown. Objectives To identify and integrate the echocardiographic features of CMs that can accurately predict malignancy. Methods Observational cohort

Long-Term Clinical Outcomes in Patients With Severe Tricuspid Regurgitation

Ref:  Nishiura N., et al, J Am Heart Assoc. 2023;12:e025751. DOI: 10.1161/JAHA.122.025751 BACKGROUND: The natural history and optimal interventional timing in patients with isolated severe tricuspid regurgitation (TR) have not been well studied. This study aimed to investigate long-term clinical outcomes and risk factors associated with poor prognosis in patients

Chronic HF poses additional mortality threat for patients with COVID-19

cardiology today, 7th Jan 2023, Adapted from Arutyunov GP, et al. ESC Heart Fail. 2022; doi:10.1002/ehf2.14243. Hospitalized patients with COVID-19 who have a history of chronic HF are at an increased risk for all-cause mortality, according to a study published in ESC Heart Failure. “Advanced chronic HF (NYHA classes III and IV) is

Autoimmune disorders associated with AF risk

cardiology today, 8th Jan 2023 Adapted from: Tilly MJ, et al. Europace. 2022;doi:10.1093/europace/euac244 Autoimmune disorders were associated with elevated atrial fibrillation risk, particularly in women, according to a study published in EP Europace. Using UK Biobank data from 2006 to 2022, 494,072 patients without AF (median age, 58 years; 55% women) were analyzed

Efficacy of Sacubitril/Valsartan in Hypertension

Aaqib M., et al,  American Journal of Therapeutics 29(3):p e322-e333, May/June 2022. | DOI: 10.1097/MJT.0000000000000925. Background:  Sacubitril/valsartan (LCZ696) has progressed to be one of the most promising medication since its approval for chronic heart failure with reduced ejection fraction. Recent data have suggested a superior blood pressure control with LCZ696. Data Sources:  Randomized controlled